Will Taking Delta-8 Interfere with My Prescription Medications?

As more people are beginning to find ways to bring delta-8 into their daily routines, we are getting asked a lot of questions about how to take it properly for the most effective and enjoyable results. 

There is a lot to know about dosing, timing, and choosing the right delivery method. 

However, a more important topic relates to taking delta-8 while on some sort of prescription medication.

While delta-8, much like CBD, is generally considered safe, it’s possible that this cannabinoid can interact with certain medications. 

We all know the importance of being aware of potential interactions so that we don’t accidentally experience harm while trying to maintain a safe daily routine.  

That’s why we’re going to share what’s known so far about using a delta-8 product, be it in an edible, a tincture, a vape oil, a capsule, a beverage, a flower-base, or even topical form while on prescription medication(s).

What We Can Say About Delta-8 So Far

What We Can Say About Delta-8 So Far

The cannabidiol market has been hugely popular for more than ten years, and during this time, we’ve acquired many scientific studies about its various effects. 

This means we know a great deal about how cannabidiol is processed and metabolized by the body, as well as how it is used for various effects.  

One thing we know about CBD is that it has been found to inhibit CYP3A4, the enzyme that is in charge of breaking down a lot of popular medications in the body so that they can leave the system. 

This metabolite is crucial in order to ensure that when we take the next dose, we are not piling onto what is already in the body to the point of potential overdose. 

This information is why we recommend you talk to a doctor before taking cannabidiol if on one or more prescription meds.

So, what about delta-8 then?  

Well, each cannabinoid is processed differently. 

Also, this particular type is so new to the scene and our industry in general, we just don’t have access to any studies about how it metabolizes in the system. 

Of course, in the future, we’ll likely find researchers seeking out this specific information, but that time has not yet come.

However, what we can do is talk about delta-9 THC potential effects on medications. 

Delta-8 is degraded delta-9, sharing a lot in common with its big sister compound, and being simply a milder version.

Therefore, we can apply some information about delta-9 to delta-8 when it comes to this topic just to be on the safe side.

Relationship Between THC and Prescription Drugs

Relationship Between THC and Prescription Drugs

As it turns out, delta-9 THC can, in fact, interact negatively with certain commonly used drugs including:

  • Blood Pressure Medications
  • Immunosuppressants
  • Antidepressants
  • Opioids
  • Blood Sugar Medications
  • Benzodiazepines

We mentioned a bit earlier that CYP3A4 is a metabolite needed to break down these drugs in the system. 

If they do not clear from the body enough when it is time for the next dose, this could lead to potentially toxic levels accumulating in the system.

THC, like CBD, has been found to potentially inhibit this metabolite. 

Additionally, it may produce additive-like effects when certain drugs are taken, meaning that THC can make the overall effects of certain medications more potent.  

For instance, benzos like Xanax slow the body’s nervous system to produce a sedative-like effect and combining it with THC could cause even more sedating effects to be felt throughout the body. 

This could lead to dangerous consequences under certain circumstances, such as a person who is driving a car and finds themselves almost falling asleep at the wheel.

What to Know About Taking Delta 8 While on a Prescription

What to Know About Taking Delta 8 While on a Prescription

Technically, we can’t say the effect that delta-8 THC has on prescription medications, because despite its similarities to cannabidiol and delta-9 THC, it’s its own individual compound with its own distinctive properties.  

But, if you are feeling cautious, here are some quick tips. 

Tip #1: Ask Your Doctor 

Ask Your Doctor About Taking Delta-8 While on Medication

This is obviously the first thing you should always do is ask your doctor about the potential for an interaction. 

They are licensed, hence able to provide medical advice, which is something that we are NOT capable of doing. 

The doctor knows your unique situation and overall medical needs.

Tip #2: The Lower the Dose, the Lower the Risk 

Of course, as is the case with anything, the lower the dose of delta-8 you take while a drug is active in your body, the lower the risk of an interaction.  

Tip #3: Pay Attention to Timing 

Every drug has its peak, so consider taking delta-8 at an opposite time of day from when you take your prescription if approved by your doctor. 

If your doctor tells you no, we STRONGLY advise listening to them, as again we are not medical professionals.

This way, there is a lower chance of both substances being present in the body in high levels at the same time.

Tip #4: Observe How You Feel

Of course, you should pay close attention to how you feel, and seek medical attention if you develop concerning symptoms.

Tip #5: Stay Away from Alcohol 

Stay Away from Alcohol When Taking Delta-8 and Medication

Alcohol is also known to produce interactions with many medications, so if you are taking delta-8 while on a prescription, avoid drinking until the next day.

Final Thoughts on Adverse Effects of Delta-8 

Delta-8 THC is a newly discovered cannabinoid that we’re still learning a lot about, which is why we can’t yet say whether or not it’s safe to take while on a prescription medication. 

What we can say is that it’s best to talk to your doctor before combining the two. 

Again, as we simply cannot stress this enough, they can give you personalized medical advice that can help you make the best/informed decision for your health.

19th Jun 2022

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